| 8-羟基脱氧鸟苷检测方法的研究进展 |
| |
| 引用本文： | 刘胜林.8-羟基脱氧鸟苷检测方法的研究进展[J].医学综述,2006,12(17):1073-1074. |
| |
| 作者姓名： | 刘胜林 |
| |
| 作者单位： | 天津西青医院检验科,天津,300380 |
| |
| 摘 要： | 活性氧基团引起的氧化损伤在许多慢性疾病中起着重要作用,8-羟基脱氧鸟苷(8-OHDG)是DNA氧化损伤的修饰产物之一,可以通过高灵敏度、高选择性的检测手段来检测,目前已成为DNA氧化损伤中最常采用的生物标志物。本文主要介绍其来源、检测方法及在医学上的应用。
|
| 关 键 词： | 8-羟基脱氧鸟苷 DNA氧化损伤 检测 |
| 文章编号： | 1006-2084（2006）17-1073-02 |
| 收稿时间： | 2006-01-10 |
| 修稿时间： | 2006-07-27 |
The Progress of 8-hydroxy-2'-deoxyguanosine Detecting Method |
| |
| LIU Sheng-lin.The Progress of 8-hydroxy-2''''-deoxyguanosine Detecting Method[J].Medical Recapitulate,2006,12(17):1073-1074. |
| |
| Authors: | LIU Sheng-lin |
| |
| Institution: | The Department of Examination, Xiqing Hospital in Tianjin, 300380, China |
| |
| Abstract: | Oxidative damage from reactive oxygen species including free radicals has been considered to play a vital role in many chronic diseases.8-hydroxy-2′deoxyguanosine(8-OHDG) is one of modified products resulting from DNA oxidative damage,which can be detected by methods with high sensitivity and high selectivity,and is a common used biomarker in detecting DNA oxidative damage.This paper introduces the source,detecting method and apllication of 8-OHDG. |
| |
| Keywords: | 8-hydroxy-2′-deoxyguanosine DNA Oxidative damage Detection |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
