Inhibition of interleukin-4 production in activated T cells via the downregulation of AP-1/NF-AT activation by N-lauroyl-D-erythro-sphingosine and N-lauroyl-D-erythro-C20-sphingosine |
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| Authors: | Park Jin Kim Seung Hyun Li Qian Chang Young-Tae Kim Tae Sung |
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| Affiliation: | School of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea. |
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| Abstract: | |
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| Keywords: | AP-1, activating protein-1 BECS, N-butyryl- smallcaps" >d-erythro-C20-sphingosine BES, N-butyryl- smallcaps" >d-erythro-sphingosine ELISA, enzyme-linked immunosorbent assay EMSA, electrophoretic mobility shift assay IL, interleukin KLH, keyhole limpet hemacyanin LECS, N-lauroyl- smallcaps" >d-erythro-C20-sphingosine LES, N-lauroyl- smallcaps" >d-erythro-sphingosine NF-AT, nuclear factor of activated T cell PKC, protein kinase C PMA, phorbol 12-myristate 13-acetate |
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