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Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders
Authors:Rosen Rachel  Johnston Nikki  Hart Kristen  Khatwa Umakanth  Katz Eliot  Nurko Samuel
Institution:a Center for Motility and Functional Gastrointestinal Disorders, Children’s Hospital Boston, Boston, MA
b Division of Pulmonary Medicine, Children’s Hospital Boston, Boston, MA
c Department of Otolaryngology and Communication Services, Medical College of Wisconsin, Milwaukee, WI
Abstract:The aim of the study was to determine if children with chronic cough or wheezing and with more full-column, nonacid reflux have a higher likelihood of a positive bronchoalveolar lavage fluid culture. In a prospective study of 46 children with cough who were undergoing endoscopy, multichannel intraluminal impedance testing, and bronchoscopy, we found that patients who had a positive culture had significantly more full-column, nonacid gastroesophageal reflux than those who had a negative culture.
Keywords:MII  Multichannel intraluminal impedance
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