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Sumatriptan Relieves Migrainelike Headaches Associated With Carbon Monoxide Exposure
Authors:Dr.,Richard B. Lipton,MD    Cynthia Mazer,MD,   Lawrence C. Newman,MD,   Seymour Solomon,MD
Affiliation:Department of Neurology, Montefiore Medical Center;Albert Einstein College of Medicine and the Headache Unit, Bronx, NY.Department of Epidemiology and Social Medicine at Montefiore Medical Center and Innovative Medical Research, Stamford, Conn
Abstract:We report a 58-year-old woman with long-standing migraine who developed a pattern of weekend headaches which occurred only while staying at her Connecticut vacation home The headaches promptly responded to sumatriptan. Investigation revealed a high carbon monoxide level in her home due to a defective furnace. Replacing the furnace eliminated the headaches. This case highlights the importance of searching for secondary causes of headache even in patients responsive to sumatriptan. It also suggests that carbon monoxide may trigger headaches mediated by trigeminovascular inflammation.
Keywords:migraine    sumatriptan    carbon monoxide
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