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Implication of intracellular ROS formation,caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells
Authors:Dong Yeok Shin  Gi Young Kim  Wei Li  Byung Tae Choi  Nam Deuk Kim  Ho Sung Kang  Yung Hyun Choi
Affiliation:1. Department of Biochemistry, Dongeui University College of Oriental Medicine, Busan 614-052, South Korea;2. Department of Molecular Biology, College of Natural Sciences, Pusan National University, Pusan 609-735, South Korea;3. Faculty of Applied Marine Science, Cheju National University, Jeju Special Self-Governing Province, Jeju 690-756, South Korea;4. College of Chinese Material Medicine, Jilin Agricultural University, Changchun 130118, Jilin Province, PR China;5. Department of Anatomy, Graduate School of Oriental Medicine, Pusan National University, Pusan 609-735, South Korea;6. Division of Pharmacy, College of Pharmacy, Research Institute for Drug Development, Pusan National University, Pusan 609-735, South Korea;g Department of Biomaterial Control (BK21 Program), Dongeui University Graduate School, Busan 614-052, South Korea
Abstract:
Keywords:Platycodon D   Apoptosis   Egr-1   ROS   MMP
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