Les dangers de l’hypothermie thérapeutique |
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Authors: | G Francony P DecletyP Bouzat J PicardJ-F Payen |
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Institution: | Pôle anesthésie–réanimation, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France |
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Abstract: | Therapeutic hypothermia (less than 35 °C) is a promising strategy to improve neuroprotection after severe brain injury. Except in patients resuscitated from cardiac arrest, its effectiveness has not yet been demonstrated. Therapeutic hypothermia results in various side effects, including cardiovascular, hydroelectrolytic and infectious disorders, which could explain, in part, the lack of conclusive clinical studies. These hazards are associated with practical difficulties to induce and maintain targeted hypothermia and with rewarming management. An improvement in the techniques for achieving targeted hypothermia, more knowledge about side effects and further randomized clinical trials are needed before recommending the use of therapeutic hypothermia for patients with severe traumatic brain injury. |
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Keywords: | Hypothermie thé rapeutique Traumatisme crâ nien Agression cé ré brale Effets secondaires |
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