纯钛种植体表面纳米含氟磷灰石涂层的构建和表征

目的：在纯钛表面构建纳米含氟磷灰石涂层并进行性能表征。方法：采用溶胶凝胶法在纯钛表面构建纳米级含氟磷灰石涂层，用X线衍射、X线光电子能谱、扫描电镜和溶解度测试表征其晶体结构、化学组成、表面形貌、厚度以及化学稳定性；用体外成骨细胞培养评价其生物活性。结果：该涂层具有良好的晶体结构和均匀的纳米级表面形貌，化学稳定性理想。体外成骨细胞培养显示其具有良好的生物活性。结论：本实验构建的涂层具有良好的性能和应用前景。

The Construction and Characterization of Nano-FHA Bioceramic Coating on Titanium Surface

Objective:This research was aimed at the construction and characterization of nano-FHA bioceramic coating on titanium surface.Methods:Nano-FHA coating was constructed on the surface of commercially pure titanium by sol-gel route.X-ray diffraction(XRD),X-ray photoelectronic spectrum(XPS),scanning electromicroscope(SEM)and dissolution test was employed to characterize the obtained coating.In vitro cellular responses of osteoblasts to the coating were also evaluated by MTT assay,ALP assay and SEM observation.Conventional HA coatings and commercially pure titanium(cpTi)were taken as control.Results:The nano-FHA bioceramic coating has good crystallization and homogeneous,nano-scale surface morphology.The dissolution rate of the coating is favorable.The in vitro osteoblasts culture exhibits satisfactory bioactivity.Conclusion:The nano-FHA bioceramic coating on titanium surface has promising prospects in the future clinical application.