Expression of mouse Tbx2 gene in normal and malignant melanophores by RT-PCR |
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Authors: | Bao-guo Liu fang-qun Han CR Goding |
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Affiliation: | (1) Department of Surgical Oncology, Beijing Cancer Hospital; School of Oncology, Beijing Medical University, 100036 Beijing, China;(2) Marie Curie Cancer Research Institute, RH8 OTL Oxted, Surrey, UK |
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Abstract: | Objective: To observe the expression of mouse Tbx2 gene in normal and malignant melanophore. Methods: The normal and malignant cells were used to extract total RNA. The expression of the Tbx2 gene was detected by RT-PCR. Results: No expression of the Tbx2 gene in the normal melanocytes was noted, but all malignant cells showed expression of the Tbx2 gene. Conclusion: Tbx2 plays a critical role during the development of the malignant cells. |
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Keywords: | Gene amplification Gene expression Malignant cell Tbx2 |
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