| 氟卡尼与奎尼丁对阵发性心房颤动的远期疗效比较 |
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| 引用本文： | 王乐信,孙静平. 氟卡尼与奎尼丁对阵发性心房颤动的远期疗效比较[J]. 中国循环杂志, 1993, 0(1) |
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| 作者姓名： | 王乐信 孙静平 |
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| 作者单位： | 中国人民解放军总医院，中国人民解放军总医院 北京医科大学第一医院心内科 |
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| 摘 要： | 以氟卡尼治疗阵发性心房颤动(简称房颤)26例,并与24例服奎尼丁者对比。平均随访1年发现,氟卡尼1个月、6个月及1年的有效率分别为46.2%,65.6%和65.6%。而奎尼丁组的有效率则分别为41.7%、50.0%和33.3%。本观察表明,氟卡尼是预防阵发性房颤的有效药物,其1年有效率高于奎尼丁。
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| 关 键 词： | 氟卡尼 奎尼丁 阵发性心房颤动 |
LONG-TERM EFFECT OF FLECAINIDE IN THE PREVENTION OF PAROXYSMAL ATRIAL FIBRILLATION |
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| Wang Le-Sing,Sun Jing-Ping. LONG-TERM EFFECT OF FLECAINIDE IN THE PREVENTION OF PAROXYSMAL ATRIAL FIBRILLATION[J]. Chinese Circulation Journal, 1993, 0(1) |
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| Authors: | Wang Le-Sing Sun Jing-Ping |
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| Affiliation: | Wang Le-Sing~*,Sun Jing-Ping. Department of Cardiology,Great Wall Hospital,Beijing |
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| Abstract: | The efficacy of flecainide in the prevention of paroxysmal atrial fibrillation was studied and compared with quinidine. 26 patients with weekly attacks during the last 3 months were treated with flecainide 100 mg b.i.d, and monitored by ECG and questionnaire every month. Abolition of the attacks of atrial fibrillation occurred in 46.2%, 65.6% and 65.6% of the patients at the end of the 1st, 6th and 12th month, respectively. The figures of the 24 patients treated with quinidine were 41.7%, 50.0% and 33.3% (p<0.05), respectively. 11.6% of the flecainide-treated patients and 25% of the quinidine-treated patients experienced side effects at the end of the study.We conclude that flecainide suppresses paroxysmal atrial fibrillation more effectively than quinidine in long-term treatment. |
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| Keywords: | Flecainide Quinidine Atrial fibrillation |
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