Blood corticosterone and resistance to hypoxia during operant conditioning and development of learned helplessness

Operant conditioning under conditions of uncertain behavioral environment was accompanied by a significant elevation of blood corticosterone, high exploratory activity, and increased resistance to hypoxia. The blood content of corticosterone and exploratory activity significantly decreased in rats developing learned helplessness, but their resistance to hypoxia increased in comparison with that during learning. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No.7, pp. 29–31, July, 1999