奥曲肽治疗肝硬化并发上消化道出血临床分析

目的:观察奥曲肽治疗肝硬化并发上消化道出血的疗效.方法:将81例肝硬化并发上消化道出血患者分为对照组(凝血酶与奥美拉唑等治疗,35例)和观察组(在此基础治疗上加用奥曲肽,46例),比较两组输血量、再出血发生率(48h)、病死率、住院时间、不良反应发生率等.结果:观察组再出血发生率显著低于对照组,住院时间显著少于对照组,两组输血量、不良反应发生率及病死率差异无显著性.结论:奥曲肽治疗肝硬化上消化道出血,能有效预防消化道再出血发生率并缩短住院时间.

Clinical analysis of octreotide treatment of upper gastrointestinal hemorrhage in patients with liver cirrhosis

Objective：To observe the curative effect and nursing of upper gastrointestinal hemorrhage patients with liver cirrhosis.Methods：81 liver cirrhosis cases with upper gastrointestinal hemorrhage were randomly divided into control group（35 cases） treated with thrombin and omeprazole,and observe group（46 cases） treated with additional octreotide.Transfusion,rebleeding rate（48h）,mortality,length of stay,adverse reaction rates of two groups were compared.Results：The rebleeding rate（48h）,length of stay were shorter in the observe group than in the control group.Transfusion,adverse reaction rates and mortality of two groups had not difference.Conclusion： Application of octreotide in the treatment of upper gastrointestinal bleeding in liver cirrhosis can effectively shorten the hospitalization days and prevent rebleeding.