| 参地糖脉宁胶囊的质量标准研究 |
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| 引用本文： | 葛勤,黄彩河. 参地糖脉宁胶囊的质量标准研究[J]. 中国药房, 2002, 13(3): 169-171 |
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| 作者姓名： | 葛勤 黄彩河 |
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| 作者单位： | 第三军医大学新桥医院,重庆市,400037 |
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| 摘 要： | 目的 :对参地糖脉宁胶囊中的丹参、生地、川芎、大黄等成分进行定性鉴别 ,同时测定该制剂主药丹参的有效成分丹参酮ⅡA 的含量。方法 :采用薄层层析进行定性 ,用固相萃取 -一阶导数紫外分光光度法进行丹参酮ⅡA 含量测定 ,色谱柱为硅胶柱 (内径1 1cm ) ,流动相为二氯甲烷 -甲醇 (8∶2) ,检测波长为280nm。结果 :丹参酮ⅡA 在1 6～8μg/ml范围内呈线性关系 ,r=0 9999 ,平均回收率为96 13 % ,RSD=0 80 %。结论 :本方法简便、稳定、准确 ,能有效地控制该制剂的质量
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| 关 键 词： | 参地糖脉宁胶囊 丹参酮ⅡA 薄层层析 固相萃取-一阶导数分光光度法 |
| 文章编号： | 1001-0408(2002)03-0169-03 |
| 修稿时间： | 2001-03-15 |
Study on Quality Standard for Shendi Tangmaining Capsules |
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| GE Qin,HUANG Caihe. Study on Quality Standard for Shendi Tangmaining Capsules[J]. China Pharmacy, 2002, 13(3): 169-171 |
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| Authors: | GE Qin HUANG Caihe |
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| Abstract: | OBJECTIVE:To identify Salvia miltiorrhiza,Rehmannia,Chuangxion rhizome,rhubarb and to determine the content of tanshinone Ⅱ A,as an efficacious composition,in Shendi Tangmaining capsules.METHODS:TLC and SPE-UV were used.The SPE-UV method was performed with silica gel column(1.1cm).The mobile phase consisted of dichloromethane-me_thanol(8∶2).The detected wavelength was 280nm.RESULTS:In the SPE-UV method,the standard curve for tanshinone Ⅱ A was linear in the range of 1.6～8μg/ml(r=0.9 999).The average recovery was 96.13% with RSD=0.80%.CONCLUSION:The method is simple,rapid and reliable for quality control of the capsules. |
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| Keywords: | Shendi Tangmaining capsule tanshinone Ⅱ A TLC SPE-UV |
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