Relevance of Pulmonary Alveolar Echinococcosis |
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| Affiliation: | 1. Ataturk University, Medical Faculty, Department of Thoracic Surgery, Erzurum, Turkey;2. Ataturk University, Medical Faculty, Department of Radiology, Erzurum, Turkey;3. Ataturk University, Medical Faculty, Department of Internal Medicine, Erzurum, Turkey;4. Ataturk University, Medical Faculty, Department of General Surgery, Erzurum, Turkey;5. Ataturk University, Medical Faculty, Department of Pathology, Erzurum, Turkey;6. Ataturk University, Medical Faculty, Department of Infectious Diseases and Clinical Microbiology, Erzurum, Turkey;7. Ataturk University, Medical Faculty, Department of Pulmonary Diseases, Erzurum, Turkey;1. Unidad de Fibrosis Quística y Bronquiectasias, Servicio de Neumología, Hospital Universitario La Paz, Madrid, España;2. Unidad de Fibrosis Quística, Servicio de Neumología, Hospital Universitario Ramón y Cajal, Madrid, España;1. Sección de Neumología, Hospital General de La Palma, Breña Alta, Santa Cruz de Tenerife, España;2. Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Área de Genética, San Cristóbal de la Laguna, Santa Cruz de Tenerife, España;1. Unidad de Enfermedades Infecciosas, Hospital Universitari Son Espases, Palma de Mallorca, Spain;2. Institut d’Investigació Sanitària Illes Balears (IdISBa), Palma de Mallorca, Spain;3. Servicio de Neumología e Instituto de Investigación, Hospital Universitario de la Princesa (IISP), Universidad Autónoma de Madrid, Madrid, Spain;4. Methodological and Scientific Consultant of SEPAR, Spain;1. Servicio de Neumología, Hospital de Laredo, Laredo, Cantabria, España;2. Centro de Salud de Cotolino, Servicio Cántabro de Salud, Castro Urdiales, Cantabria, España;3. Centro de Salud de Santoña, Servicio Cántabro de Salud, Santoña, Cantabria, España;4. Global Health Research Group, Universidad de Cantabria-IDIVAL, Santander, Cantabria, España |
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| Abstract: | BackgroundPulmonary alveolar echinococcosis (PAE) is a chronic disease caused by Echinococcus multilocularis with very low incidence in developed countries.MethodsThis single-center, retrospective study included 34 patients who were diagnosed with PAE between January 2001 and February 2019 (15 males, 19 females, mean age: 52.4 ± 15.8 years, age range: 28–78 years) in Ataturk University Medical School, Erzurum, Turkey.ResultsThe liver was the primary involved organ in all cases. Pulmonary involvement was detected in 13.0% (34/261) of all cases with hepatic alveolar echinococcosis (AE), and three patients (8.8%) had both pulmonary metastasis and brain metastasis. The route of spread to the lungs based on radiological data was hematogeneous in 25 patients (73.5%), transdiaphragmatic in three patients (8.8%) and both hematogeneous and transdiaphragmatic in six patients (17.7%). AE showed bilateral involvement in 19 patients (55.9%), whereas only the right lung was involved in 12 patients (35.3%) and the left lung in three patients (8.8%). Of the patients, five underwent surgery due to PAE and 29 patients received medical therapy with albendazole. A total of three patients died during the follow-up period (2, 5 and 10 years after the diagnosis of PAE), while 31 patients continued with follow-up and treatment for a mean duration of 5.4 ± 3.8 years (1–14 years).ConclusionsPatients with hepatic AE must, as a matter of course, be screened for possible lung involvement. Albendazole therapy may slow down disease progression in patients with widespread pulmonary involvement who are not eligible for surgery. |
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| Keywords: | Echinococcus alveolar Lung Clinic Radiology Management Pulmón Clínica Radiología Manejo |
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