Effects on Humidification and Ventilatory Parameters of Three Single-limb Heated-wired Circuits for Non-invasive Ventilation: A Bench Study |
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| Affiliation: | 1. Department of Anesthesiology, Critical Care and Pain Medicine, Hospital Universitari i Politècnic La Fe, Valencia, Spain;2. Department of Hospital Managing, Hospital de Manises, Manises, Valencia, Spain;3. Emergency Department, Hospital General Universitario de Alicante, Alicante, Spain;4. Emergency Department, Hospital de Sagunto, Sagunto, Valencia, Spain;5. Short-stay Medical Unit, Emergency Department, Hospital General Universitario de Alicante, Alicante, Spain;6. Department of Pneumology, Hospital Universitario Ramón y Cajal, Madrid, Spain;1. Department of Pediatrics, Arizona Respiratory Center, University of Arizona, 1501 North Campbell Avenue, Tucson, AZ, USA;2. Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, Arizona Respiratory Center, University of Arizona, 1501 North Campbell Avenue, Tucson, AZ, USA;3. Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, Arizona Respiratory Center, University of Arizona, 1501 North Campbell Avenue, Room 2342D, Tucson, AZ 85724, USA;1. Sleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain;2. Medicine Department, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain;3. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain;4. Pneumology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain;5. Group of Translational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova y Santa Maria, IRB Lleida, Lleida, Spain;6. Sleep Unit, Dr. J Terán Santos. Pneumology Department. Hospital Universitario de Burgos. Castilla - Leon, Spain;7. IIS Fundación Jiménez Díaz, Madrid, Spain;8. Pneumology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain;9. Sleep Unit, Hospital Universitario de Araba, OSI Araba, Vitoria Gasteiz, Spain;11. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain;22. Instituto de Investigación Bioaraba, OSI Araba Hospital Universitario, Vitoria, Spain;33. Facultad de Medicina, Departamento de Medicina, Universidad del País Vasco, UPV/EHU, País Vasco, Spain;44. Centro de Investigación Biomédica en Redde Enfermedades Respiratorias (CIBERES), Madrid, Spain;55. SleepUnit, Pneumology Department, Hospital Universitario de Burgos, Burgos, Castilla-León, Spain;66. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain;77. Group of Translational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova y Santa Maria, IRB Lleida, Lleida, Spain;88. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain;99. Pneumology Department, Hospital San Pedro de Alcántara, Cáceres, Spain;1010. Centro deInvestigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain;1111. Pneumology Department, Hospital Universitario Clinic-IDIBAPS, Barcelona, Spain;1. Clínica Universidad de Navarra, Madrid, España;2. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, CIBERES, Instituto de Salud Carlos III, España;3. Hospital de la Santa Creu i Sant Pau, Barcelona, España;4. Coordinador Área de Oncología Torácica, SEPAR, España;5. Clínica Universidad de Navarra, Pamplona, España;1. Department of Respiratory Disease, Hiroshima Red Cross Hospital & Atomic Bomb Survivors Hospital, Naka-ku, Hiroshima, Japan;2. Department of Molecular and Internal Medicine, Institute of Biomedical & Health Sciences, Hiroshima University, Minami-ku, Hiroshima, Japan |
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| Abstract: | BackgroundThe objective of this study was to evaluate the effects of three single-limb heated wired circuits (SLHWC) for NIV, on ventilatory parameters and humidification performance in a simulation lung model.MethodsThree SLHWC compatible with the MR-850 Heated Humidifier (HH) (Fisher & Paykel, Auckland, New Zealand) were tested: RT-319 (FP) (Fisher & Paykel, Auckland, New Zealand), Respironics 1045770 (RP) (DEAS, Castel Bolognese, Italy) and Intersurgical B/SYS 5809001 (IT) (Intersurgical, Wokingham, UK). A Bipap Vision ventilator (Philips Respironics, Murrysville, PA, USA) in pressure control ventilation (PCV) connected to a test lung was used for simulation. Each SHWC performance was evaluated in four ventilatory conditions: IPAP of 15 cm H2O with FiO2 0.3 and 1, respectively; and, IPAP of 25 cm H2O with FiO2 0.3 and 1, respectively. EPAP was set at 5 cm H2O. Hygrometric and ventilatory measurements including: relative humidity (RH), temperature (T), Pplat, PIP, PEEP, peak inspiratory flow (PIF), and tidal volume (Vt) were measured.ResultsIn each FiO2 group absolute humidity (AH) was similar with FP regardless of the IPAP level employed compared to IT and RP (P < .001). Except for RP at FiO2 0.3, AH increased significantly in IT and RP groups as IPAP increased (P < .001). PIP, Pplat, PEEP, PIF, and Vt values were significantly higher with FP and RP in each FiO2 group compared to IT (P < .001).ConclusionsHumidification performance varied significantly among the three circuits, being FP the only one able to maintain stable AH values during the study with no influence on ventilatory parameters. |
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| Keywords: | Heated humidifiers Respiratory mechanics Humidification Non-invasive ventilation Mechanical ventilation Humidificadores calefactados Mecánica respiratoria Humidificación Ventilación no invasiva Ventilación mecánica |
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