Absence of fibula and ulna with oligodactyly,contractures, right-angle bowing of femora,abnormal facial morphology,cleft lip/palate and brain malformation in two sibs: A possible new lethal syndrome

Absence of fibulae, and unilateral absence of ulna, associated with lateral oligodactyly, and rectangular bowing of the femora are the prominent features of a lethal syndrome studied in two children of related parents. Other malformations are cleft lip and palate and posterior midline abnormalities of the brain. One similar though not identical MCA-syndrome was reported. The literature is reviewed with respect to ulno-fibular malformations.