Mechanisms of behavioral effects of potentiated morphine forms |
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Authors: | O. I. Epshtein T. A. Zapara I. F. Pavlov O. G. Simonova |
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Affiliation: | (1) Materia Medica Research-and-Production Company, Moscow;(2) Institute of Medical and Biological Cybernetics, Novosibirsk |
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Abstract: | Effects of morphine and its potentiated (homeopathic) form on rat behavior in an elevated plus-maze were studied. Combined application of potentiated and non-potentiated morphine enhanced the anxiolytic and sedative effects. Patch-clamp experiments on isolatedHelix pomatia giant neurons revealed a blocking effect of potentiated morphine on μ-receptors. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 12, pp. 619–622, December, 1999 |
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Keywords: | morphine potentiated forms behavior isolated neurons membrane currents |
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