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Mechanisms of behavioral effects of potentiated morphine forms
Authors:O. I. Epshtein  T. A. Zapara  I. F. Pavlov  O. G. Simonova
Affiliation:(1) Materia Medica Research-and-Production Company, Moscow;(2) Institute of Medical and Biological Cybernetics, Novosibirsk
Abstract:Effects of morphine and its potentiated (homeopathic) form on rat behavior in an elevated plus-maze were studied. Combined application of potentiated and non-potentiated morphine enhanced the anxiolytic and sedative effects. Patch-clamp experiments on isolatedHelix pomatia giant neurons revealed a blocking effect of potentiated morphine on μ-receptors. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 12, pp. 619–622, December, 1999
Keywords:morphine    potentiated forms    behavior    isolated neurons    membrane currents
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