| 一清胶囊抗甲型H1N1流感病毒作用 |
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| 引用本文： | 徐雄良,岳韵,刘小均,杨刚,刘浪,柯潇,郑强. 一清胶囊抗甲型H1N1流感病毒作用[J]. 中国现代应用药学, 2015, 32(9): 1056-1058 |
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| 作者姓名： | 徐雄良 岳韵 刘小均 杨刚 刘浪 柯潇 郑强 |
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| 作者单位： | 成都康弘药业集团股份有限公司国家企业技术中心，成都 610036,成都康弘药业集团股份有限公司国家企业技术中心，成都 610036,成都康弘药业集团股份有限公司国家企业技术中心，成都 610036,成都康弘药业集团股份有限公司国家企业技术中心，成都 610036,成都康弘药业集团股份有限公司国家企业技术中心，成都 610036,成都康弘药业集团股份有限公司国家企业技术中心，成都 610036,成都康弘药业集团股份有限公司国家企业技术中心，成都 610036 |
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| 摘 要： | 目的 研究一清胶囊抗甲型H1N1流感病毒作用。方法 采用小鼠气管内注入甲型流感病毒鼠肺适应株A/PR/8/34(H1N1)病毒液建立病毒感染小鼠模型，以肺指数、肺指数抑制率、小鼠累积死亡率为指标，评价一清胶囊体内抗甲型H1N1流感病毒作用。结果 7.3 g·kg-1一清胶囊(原生药)可降低病毒感染小鼠的肺脏指数(P<0.05)和小鼠感染病毒后7~9 d内的死亡率(P<0.01)。结论 一清胶囊具有明显的抗甲型H1N1流感病毒作用。
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| 关 键 词： | 一清胶囊；抗病毒；甲型H1N1流感病毒 |
| 收稿时间： | 2015-02-01 |
| 修稿时间： | 2015-09-04 |
Anti-virus Effect of Yiqing Capsule on Influenza A Subtype H1N1 |
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| XU Xiongliang,YUE Yun,LIU Xiaojun,YANG Gang,LIU Lang,KE Xiao,and ZHENG Qiang. Anti-virus Effect of Yiqing Capsule on Influenza A Subtype H1N1[J]. The Chinese Journal of Modern Applied Pharmacy, 2015, 32(9): 1056-1058 |
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| Authors: | XU Xiongliang YUE Yun LIU Xiaojun YANG Gang LIU Lang KE Xiao and ZHENG Qiang |
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| Affiliation: | National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China,National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China,National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China,National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China,National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China,National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China and National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceuticals Group Co., Ltd., Chengdu 610036, China |
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| Abstract: | OBJECTIVE To evaluate the antivirus effect of Yiqing capsule. METHODS Antivirus test in vivo of Yiqing capsule was carried out by intratracheal injection of influenza A strains A/PR/8/34 (H1N1) strain in mice. The lung index, inhibition rate of lung index and death rate of mice were measured to observe the effect of anti-influenza A virus subtype H1N1 in vivo. RESULTS The 7.3 g·kg-1 Yiqing capsule(crude) could significantly decrease the lung index of viral infected mice (P<0.05) and the mortality of 7-9?d in viral infected mice(P<0.01). CONCLUSION Yiqing capsule has good effect of anti-influenza A virus subtype H1N1 in vivo. |
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| Keywords: | Yiqing capsule anti-virus influenza A virus subtype H1N1 |
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