胸壁巨大上皮样血管肉瘤的临床病理分析

目的探讨发生于胸壁上皮样血管肉瘤的临床病理特征、病理诊断及鉴别诊断。方法对1例原发于胸壁的上皮样血管肉瘤进行组织形态学、免疫组织化学分析,并复习相关文献。结果肿瘤大体形态有主瘤结及卫星瘤节的特点,镜下观察其瘤细胞呈上皮样排列,异型性明显,免疫组化结果显示Vim强阳性,CD31阳性,CD34阳性。结论发生于胸壁的上皮样血管肉瘤较少见,术前确诊较困难,须与原发于胸膜的恶性间皮瘤、转移癌、恶性黑色素瘤等鉴别。

A Clinicopathological Study of one Epithelioid Angiosarcoma of Chest Wall

Objective To study the Clinicopathological features of epithelioid angiosarcoma（EA）and to propose its differential diagnosis.Methods one EA of Chest Wall was observed by means of HE staining,immunohistochemical staining（SP method）and review of the related literature.Results There was a characteristic which the gross morphology of tumor had primary burrknot and secondary burrknots.The tumor cells presented epithelioid features with obvious atypia and expressed CD31,CD34 and vimentin.Conclusion EA occurred in chest wall is rare malignant tumor with diagnostic difficulty,Skin contact with products that contain polyvinyl chloride causally has been reported to be related to angiosarcoma.It should be differentiated from malignant mesothelioma of pleura,carcinoma metastaticum,malignant melanoma etc.