心室壁机械感受性反射敏感性的实验研究

目的；探索一种定量判断心室壁机械感受性反射敏感性大小的方法，并观察缓冲神经对其的影响。方法；成年猫去缓冲神经前后，分别采取逐级夹闭升主动脉以提高左心室内压，观察心率和左心室内压之间的关系。结果；（１）去缓冲神经前，心率和左心室舒张末压之间存在负相关关系，而与左心室收缩压无相关性；（２）去缓冲神经后，心率和左心室舒和之间依然存在负相关关系，而与心韦缩压无相关性，且左心室舒张末压的变化引起的心率改变明

The experimental study on ventricular mechanoreceptor reflex sensitivity

To develop a measurable method of ventricular mechanoreceptor reflex sensitivity and investigate the effect of buffering nerve on it. Methods: The relationship between heart rate (HR) and left ventricular pressure(LVP) was observed in cats when LVP was lifted by ascending aorta gradationally occluded before and after sino-aortic denervation. Results: (1) HR correlated negatively with left ventricular endo-diastolic pressure(LVEDP) and no obvious relationship between HR and left ventricular systolic pressure(LVSP) before sino-aortic denervation; (2) After denervation, HR still correlated negatively with LVEDP, and the change of HR with increase in LVEDP became larger; (3) Among cats, the change of HR with increase in LVEDP was different. Conclusion: The change of HR with increase in LVEDP can represent the sensitivity of ventricular mechanoreceptor reflex, it was different among cats and affected by afferent of baroreflex.