老年人肥胖与脂类代谢紊乱、心脑血管疾病危险因素相关性的研究

根据体重指数（ＢＭＩ），将６２３例老年人分为消瘦、正常、超重、肥胖４组（ＢＭＩ＜２０、２０～、２４～及２８～）。检测其身高、体重、血压、空腹血糖、胆固醇、甘油三酯及超声心动图。发现随ＢＭＩ增加，抽测人群平均年龄下降；超重与肥胖者的胆固醇及甘油三酯水平明显增加（Ｐ均＜０．０５）；体重、ＢＭＩ、收缩压及血糖均与胆固醇及甘油三酯呈明显正相关（Ｐ＜０．０５及０．００１），舒张压与胆固醇呈正相关（Ｐ＜０．０１）。多元逐步回归示除收缩压外，胆固醇、甘油三酯、血糖及舒张压均与ＢＭＩ呈正相关，均是影响ＢＭＩ的独立因素。结果提示肥胖与糖代谢及脂代谢紊乱密切相关。

Relationship among Senile Obesity,Lipid and Lipoprotein Metabolism and Cardiovascular Disease in Old Subjects

The healthy status of 623 elderly subjects aged 60 years and above was examined including height,weight,blood pressure,fasting blood sugar(BS),total cholesterol(TC),triglyceride(TG),electrocardiogram and echocardiogram. The subjects were divided into four subgroups according to their body mass index(BMI): thin (BMIP all<0.05). There were positive correlations among TC,TGand weight,BMI,systolic blood pressure and BS(P <0.05 and 0.001 respectively); negative correlation between TCand diastolic blood pressure(P <0.01). Stepwise multivariate regression analysis disclosed that TC,TG,BSand DBPall alone and jointly positively correlated with BMIexcept SBP. It was suggested that obesity is one of the important risk factors for cardiovascular disease.