国际糖尿病联盟工作定义在中老年代谢综合征人群中的应用

对1136例于2009年3月至5月体检的40岁以上中老年人的代谢综合征等指标进行分析.随着年龄增加,总体脂参数、局部体脂参数及血压、血糖水平和血清尿酸均有增加,血脂紊乱加重(P<0.01);代谢综合征高发,总体为15.1%(171/1136),且随着年龄增长而升高(P<0.01),其中以中心性肥胖+血压异常+血脂异常组合比例最高,占40.9%(70/171);腰臀比、体重指数、血清尿酸与代谢综合征密切相关.

Prevalence of the metabolic syndrome in middle-aged and elderly individuals

Totally 1136 individuals aged over 40 underwent health check up in March to May 2009. Fasting blood glucose, 2-h post-challenge blood glucose, glycated hemoglobin A1c ( HbA1c), total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and serum uric acid were measured. The diagnosis of metabolic syndrome was based on the International Diabetes Federation Criteria. The results shows that total body fat, region body fat indices, blood pressure, blood glucose and serum uric acid levels increased with the age ( P < 0.01) . The prevalence rate of metabolic syndrome in this group of individuals were 15. 1% (171/1136) , and increased with age (P<0.01). The most common combination of metabolic syndrome was central obesity-hypertension-dyslipidemia (40. 9% , 70/171). Unconditional logistic regression revealed that waist-hip-ratio, body mass index and uric acid were the risk factors for metabolic syndrome.