| 血管旁脂肪组织与心血管疾病的关系 |
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| 引用本文： | 王亚萍,田刚. 血管旁脂肪组织与心血管疾病的关系[J]. 心血管病学进展, 2009, 30(6) |
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| 作者姓名： | 王亚萍 田刚 |
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| 作者单位： | 西安交通大学医学院第一附属医院心内科,陕西,西安,710061 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 血管旁脂肪组织与血管在组织学上密切相关,近期研究表明它不只是惰性的能量储存器官,还是个活跃的内分泌器官,可分泌血管活性因子调节血管张力,并释放炎性因子等参与血管炎症、内皮损伤,从而与高血压、动脉粥样硬化等心血管疾病有密切的关系。现就血管旁脂肪组织参与高血压、动脉粥样硬化的机制作一综述。
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| 关 键 词： | 血管旁脂肪组织 血管外膜依赖性舒张因子 炎症 高血压 动脉粥样硬化 |
Perivascular Adipose Tissue and Cardiovascular Diseases |
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| WANG Ya-ping,TIAN Gang. Perivascular Adipose Tissue and Cardiovascular Diseases[J]. Advances in Cardiovascular Diseases, 2009, 30(6) |
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| Authors: | WANG Ya-ping TIAN Gang |
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| Affiliation: | WANG Ya-ping; TIAN Gang(Department of Cardiology; The First Affiliated Hospital of Medical College of Xi'an Jjiaotong University; Xi'an 710061; China); |
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| Abstract: | Perivascular adipose tissue (PVAT) is closely related to blood vessels in histology. Recent studies have indicated that it is not only a passive reservoir for energy storage, but also a highly active endocrine organ. PVAT produces vasoactive substances that influence arterial tone and releases proinflammatory cytokines and chemokines that induce arterial inflammation and endothelium damage. Therefore it plays an important role in hypertension and atherosclerosis. This article is a summary of the mechanism of PVAT in both hypertension and atherosclerosis. |
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| Keywords: | perivascular adipose tissue adipocyte-derived relaxing factor inflammation hypertension atherosclerosis |
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