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美罗华联合方案治疗B细胞淋巴瘤的临床护理
引用本文:陈秀凤,杨秀玉,余甫琴. 美罗华联合方案治疗B细胞淋巴瘤的临床护理[J]. 陕西肿瘤医学, 2011, 0(1): 197-198
作者姓名:陈秀凤  杨秀玉  余甫琴
作者单位:福建省肿瘤医院淋巴瘤内科,福建福州350014
摘    要:目的:总结使用美罗华治疗B细胞非霍奇金氏淋巴瘤的临床护理要点。方法:护理67例美罗华联合方案治疗的B细胞淋巴瘤患者,观察其治疗效果以及不良反应,总结相应的临床护理措施。结果:67例患者中,CR44例(65.7%),PR17例(25.4%),总有效率91.0%。不良反应主要为:骨髓抑制1—2度50.7%、3—4度44.7%,2例出现荨麻疹,4例出现寒战、发热,2例出现血压下降。结论:美罗华联合方案治疗B细胞淋巴瘤效果显著并且安全,护理要点为严格掌握静脉滴注的速度,加强对过敏、畏冷、发热以及血液系统等不良反应的观察及护理。

关 键 词:美罗华  B细胞非霍奇金氏淋巴瘤  护理

Clinical nursing of combined Rituximab chemotherapy for B cell non - hodgkins lymphoma
Affiliation:CHEN Xiu - feng, YANG Xiu - yu, YU Fu - qin (Department of Medical Oncology, Fujian Provincial Tumor Hospital, Fuzhou 350014, China.)
Abstract:Objective:To summarize the key point of nursing for combined Rituximab chemotherapy for B cell non - hodgkin's lymphoma(NHL). Methods: Total of 67 patients with B cell NHL received combined Rituximab chemotherapy, and were investigated the therapeutic and side - effect, explore the nursing measures. Results : Of 67 patients 44 patients(65.7% )achieved complete remission, 17 patients (25.4%) achieved partial reission ,with a response rate of 91.0%. Adverse reactions mainly included urticaria(2 patients) , shiver and fever(4 patients) , fall in blood pressure ( 2 patients ), myelosuppression ( grade I - II , 34 patients, 50.7% ; grade m - IV, 34 patients, 44. % ). Conclusion : Combined Rituximab chemotherapy is highly effetive and safe for B cell NHL, the key point of nursing is handling the velocity of intravenously guttae;paying attention to the adverse reactions of allergic reactions, shiver, fever and myelosuppression.
Keywords:B cell non- hodgking lymphoma  rituximab  nursing
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