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鳞状上皮细胞癌抗原检测在宫颈鳞癌中的临床意义
引用本文:王喜青,邓敬兰,汪静,沈建军,梁晓燕.鳞状上皮细胞癌抗原检测在宫颈鳞癌中的临床意义[J].陕西肿瘤医学,2011(2):336-337.
作者姓名:王喜青  邓敬兰  汪静  沈建军  梁晓燕
作者单位:第四军医大学西京医院核医学科,陕西西安710032
摘    要:目的:探讨血清鳞状上皮细胞癌相关抗原(SCC—Ag)检测在宫颈鳞癌中的临床意义。方法:用全自动化学发光分析仪检测107例不同临床分期宫颈鳞癌患者血清SCC—Ag的含量,并与对照组进行对比分析。结果:SCC-Ag阳性率随临床分期进展而增高,不同分组之间呈显著性差异(P〈0.01)。SCC—Ag在宫颈鳞癌的表达与临床分期有关(P〈0.01)。结论:SCC—Ag是宫颈鳞癌较特异的肿瘤标志物,对宫颈鳞癌的辅助诊断、治疗效果及预后的判断有较大的价值。

关 键 词:鳞状上皮细胞癌抗原  宫颈鳞癌  诊断

The clinic significance of SCC -Ag testing in serum of squamous cell cancer patients
Institution:WANG Xi - qing, DENG Jing - lan, WANG Jing, SHEN Jian -jun, LIANG Xiao - yan ( Department of Nuclear Medicine, Xijing Hospital, The Fourth Military Medical University , Xi'an ,710032, China.)
Abstract:Objective:To investigate the clinical significance of squamous cell carcinoma antigen (SCC- Ag) as a tumor marker in the diagnosis and clinical monitor of cervical squamous cell carcinoma, and the relationship between serum SCC - Ag level and clinical stage of cervical cancer. Methods: Squamous cell carcinoma antigen ( SCC - Ag) was measured in serum from 107 cervical squamous cell carcinoma patients and control group. Results:Serum SCC - Ag level in patients with squamous cell carcinoma of cervix increased with elevation of clinical stage ( P 〈 0.01 ). Conclusion: SCC - Ag is a specific tumor marker of the squamous cell carcinoma of cervix. SCC - Ag can be used as a marker for adjuvant diagnosis of cervical cancer and to estimate the surgical efficacy and as a clinical monitor.
Keywords:SCC - Ag  cervical squamous cell carcinoma  diagnosis
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