辽宁省居民高血压合并糖尿病患病率及影响因素分析

目的 了解辽宁省居民高血压合并糖尿病患病情况，并探讨其相关危险因素，为制定有针对性的防制策略和措施提供科学依据。方法 采用分层整群随机抽样的方法选取6个区县作为研究现场，对5397名年龄在35~75岁居民进行问卷调查、体格检查及实验室检测。根据高血压和/或糖尿病诊断标准，将调查对象分为非高血压非糖尿病组（28274例）、高血压非糖尿病组（15614例）、糖尿病非高血压组（3450例）及高血压合并糖尿病组（6159例）。应用SPSS 22.0软件进行统计分析，计量资料采用t检验，计数资料采用卡方检验，利用logistic回归模型进行危险因素分析。结果 辽宁省高血压合并糖尿病患病率为11.51%，其中男性患病率10.97%，女性患病率11.99%。多因素分析结果显示，女性（OR=1.371，95%CI=1.277~1.471）、高年龄（45~54岁组:OR=2.207，95%CI=1.987~2.452；55~64岁组:OR=4.388，95%CI=3.960~4.862；65~75岁组:OR=6.194，95%CI=5.553~6.909）、吸烟（OR=1.134，95%CI=1.039~1.238）、饮酒（OR=2.020，95%CI=1.811~2.253）、超重（OR=1.761，95%CI=1.637~1.893）、肥胖（OR=3.580，95%CI=3.290~3.895）、TC偏高（OR=1.433，95%CI=1.261~1.629）、TG偏高（OR=2.048，95%CI=1.905~2.200）、LDL-C偏高（OR=1.424，95%CI=1.226~1.654）、HDL-C偏低（OR=1.166，95%CI=1.081~1.258）均为高血压合并糖尿病患者的危险因素（P<0.01），高收入（OR=0.746，95%CI=0.672~0.829）为保护性因素（P<0.01）。结论 辽宁省35~75岁居民高血压合并糖尿病患病率较高，应加强对重点人群的干预，提倡健康生活方式，戒烟限酒，降低高血压合并糖尿病的患病风险。

Prevalence and risk factors of hypertension combined with diabetes in Liaoning province

Abstract:Objective To analyze the prevalence and risk factors of hypertension combined with diabetes in Liaoning province, and to provide evidence of formulating relevant prevention and control strategies. Methods A multi-stage stratified random cluster sampling method was used to investigate the residents of 6 counties in Liaoning province. A total of 53 497 adults aged 35-75 years were surveyed.Questionnaire survey and related measurements were conducted. According to the diagnostic criteria of hypertension and diabetes, the study population was divided into control group(n=28 274), hypertension group(n=15 614), diabetes group(n=3 450) and hypertension-diabetes group(n=6 159).All statistical analyses were performed using SPSS 22.0 for t test, chi-square test and multi-classification logistic regression. Results The prevalence hypertension combined with diabetes in Liaoning province was 11.51%, of which 10.97% in males and 11.99% in females, respectively. Results of multivariate logistic regression showed that age(45～54:OR=2.207, 95%CI=1.987～2.452; 55～64:OR=4.388, 95%CI=3.960～4.862; 65～75:OR=6.194, 95%CI=5.553～6.909), female(OR=1.371, 95%CI=1.277～1.471), smoking(OR=1.134, 95%CI=1.039～1.238), drinking(OR=2.020, 95%CI=1.811～2.253), over weight(OR=1.761, 95%CI=1.637～1.893), obesity(OR=3.580, 95%CI=3.290～3.895), high triglyceride(OR=2.048, 95%CI=1.905～2.200), high total cholesterol(OR=1.433, 95%CI=1.261～1.629), high low density lipoprotein cholesterol(OR=1.424, 95%CI=1.226～1.654)and low high density lipoprotein cholesterol(OR=1.166, 95%CI=1.081～1.258)were risk factors of hypertension combined with diabetes(P<0.01). High income(OR=0.746, 95%CI=0.672～0.829)was a protective factor(P<0.01). Conclusion The prevalence of hypertension combined with diabetes in population aged 35～75 years in Liaoning province was high. A healthy lifestyle was advocated. Smoking and drinking should be limited. It is necessary to strengthen the intervention in this population in order to reduce the incidence of hypertension combined with diabetes in Liaoning province.