Biopsia cerebral estereotáctica sin marco: capacidad diagnóstica y complicaciones |
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| Institution: | 1. DENT Neurologic Institute, 3980 Sheridan Drive, Amherst, NY 14226, USA;2. DENT Neurologic Institute, Roswell Park Cancer Institute, 3980 Sheridan Drive, Buffalo, NY 14226, USA;1. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China;2. Institute of Neuroscience, Chongqing Medical University, Chongqing, China;3. Chongqing Key Laboratory of Neurobiology, Chongqing, China;1. Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, United States;2. Current affiliation: Pharmacometrics, Pfizer, Inc, Cambridge, Massachusetts, United States;3. Department of Neurology, University of Minnesota, Minneapolis, Minnesota, United States;1. Department of Neurosurgery, Gazi University Faculty of Medicine, Ankara, Turkey;2. Department of Radiology, Gazi University Faculty of Medicine, Ankara, Turkey;3. Department of Radiation Oncology, Gazi University Faculty of Medicine, Ankara, Turkey;4. Division of Pediatric Neurosurgery, Gazi University Faculty of Medicine, Ankara, Turkey;5. Department of Histology and Embryology, Hacettepe University Faculty of Medicine, Ankara, Turkey |
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| Abstract: | ObjectiveThe aim of this study was to evaluate the variables that could modify the diagnostic yield of frameless stereotactic biopsy, as well as its complications.Materials and methodThis was a retrospective study of frameless stereotactic biopsies carried out between July 2008 and December 2011 at Donostia University Hospital. The variables studied were size, distance to the cortex, contrast uptake and location.ResultsA total of 70 patients were included (75 biopsies); 39 males and 31 females with an age range between 39 and 83 years.The total diagnostic yield in our series was 97.1%. For lesions >19 mm, the technique offered a sensitivity of 95.2% (95% CI: 86.9-98.4) and specificity of 57.1% (95% CI: 25.0-84.2). The yield was lower for lesions within 17 mm of the cortex: sensitivity of 74.6% (95% CI: 62.1-84.7) and specificity of 71.4% (95% CI: 29.0-96.3).Seven (10%) patients developed complications after the first biopsy and none after the second.ConclusionsThe diagnostic yield was lower for lesions less than 2 cm in size and located superficially.In this series we did not observe an increased rate of complications after a second biopsy. |
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| Keywords: | Frameless stereotactic biopsy Diagnostic yield Complications |
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