The additional value of blood cultures in patients with complicated urinary tract infections |
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| Affiliation: | 1. Department of Internal Medicine, Division of Infectious Diseases, Centre for Infection and Immunity Amsterdam, Academic Medical Centre, Nijmegen, the Netherlands;2. Clinical Research Unit, Academic Medical Centre of the University of Amsterdam, Nijmegen, the Netherlands;3. Department of Urology, Academic Medical Centre, Nijmegen, the Netherlands;4. Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands |
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| Abstract: | We evaluated 800 hospitalized patients with a complicated urinary tract infection, from whom both a blood and a urine culture were obtained on the first day of antibiotic treatment. Urine cultures were positive in 70% of patients, and blood cultures were positive in 29%. In 7% of patients, uropathogens caused bacteraemia with a pathogen that was not isolated from urine. Receiving antibiotic therapy at the moment of hospitalization was the only factor independently associated with discordant culture results (OR, 2.06; 95% CI, 1.18–3.61). For those receiving antibiotics at the moment of hospitalization, blood cultures have additional diagnostic value over urine cultures. |
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| Keywords: | Bacteraemia culture (blood/urine) diagnostics risk factors urinary tract infection |
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