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Respiratory syncytial virus in critically ill adult patients with community-acquired respiratory failure: a prospective observational study
Affiliation:1. Department of Medical Microbiology, Utrecht, the Netherlands;2. Department of Intensive Care Medicine, Utrecht, the Netherlands;3. Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands;4. Department of Pediatrics, Medical Center Leeuwarden, Utrecht, the Netherlands;5. Department of Intensive Care, Medical Center Leeuwarden, Leeuwarden, Utrecht, the Netherlands;6. Department of Pediatric Infectious Diseases, Wilhelmina Children''s Hospital, University Medical Center Utrecht, Utrecht, the Netherlands
Abstract:The incidence of respiratory syncytial virus (RSV) and influenza virus infection was determined during three RSV seasons in 158 adult patients consecutively admitted to the intensive care unit with community-acquired respiratory failure. Nasopharyngeal swabs were tested for the presence of RSV and influenza virus by real-time polymerase chain reaction. Six patients (4%) were positive for RSV and all recovered. This finding was in sharp contrast to influenza (23 (15%) patients, 4 (17%) deaths). In conclusion, even in the midst of the RSV season, RSV is an infrequent cause of respiratory failure in adults admitted to the intensive care unit.
Keywords:Adult  influenza  intensive care unit  respiratory failure  respiratory syncytial virus
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