贵州农村老年人腹型肥胖及血脂水平对动脉硬化的交互作用

目的 探讨农村老年人腹型肥胖及血脂水平对动脉硬化的交互影响，为动脉硬化的防治提供参考依据。方法 采用多阶段抽样方法选取贵州省2个县（区）内5个乡镇共1 035名60岁及以上老年人为研究对象，进行问卷调查、现场体格检查、实验室检测和动脉硬化检测，采用SPSS 24.0软件进行χ2检验和非条件logistic回归分析贵州农村老年人腹型肥胖、血脂水平及其交互作用对动脉硬化的影响。结果 1 035名老年人中检出动脉硬化对象942人，检出率为91.01%。腹型肥胖老年人动脉硬化检出率94.25%（606人）；TG异常老年人动脉硬化检出率97.53%（158人）。多因素logistic回归分析结果显示，控制年龄、性别、婚姻状况、是否高血压等因素后，腹型肥胖者（OR = 2.018，95%CI:1.188～3.428），TG异常者（OR = 3.350，95%CI:1.148～9.774）与老年人动脉硬化患病高风险相关。交互作用分析结果显示TG×腹型肥胖对老年人发生动脉硬化存在相乘交互作用（P＜0.05），（OR = 3.526，95%CI:1.053～11.810）。结论 腹型肥胖、TG异常是动脉硬化的独立影响因素，且腹型肥胖与血脂水平对老年人患动脉硬化具有相乘交互作用。

Interaction of abdominal obesity and blood lipid levels on atherosclerosis in rural elderly of Guizhou Province

To explore the interaction of abdominal obesity and blood lipid levels on atherosclerosis in rural elderly population, so as to provide reference for the prevention and treatment of atherosclerosis. Methods A total of 1 035 elderly people aged 60 and above were selected from 5 townships in 2 counties(districts) of Guizhou Province by multi-stage sampling method. Questionnaire survey, on-site physical examination, laboratory test, and arteriosclerosis test were carried out. Chi-square test was carried out by SPSS24.0 software, and unconditional logistic regression analysis was used to explore the relationship between abdominal obesity and atherosclerosis in elderly people in rural areas of Guizhou Province for the effect of blood lipid level and its interaction on atherosclerosis. Results Among 1 035 elderly people, 942 people were diagnosed with arteriosclerosis, and the detection rate was 91.01%. The detection rate of arteriosclerosis in the elderly with abdominal obesity was 94.25%(606 patients) and that of atherosclerosis in the elderly with abnormal TG was 97.53%(158 patients). Univariate analysis showed that abdominal obesity and abnormal TG were the influencing factors of atherosclerosis(P <0.05). Multivariate logistic regression analysis showed that abdominal obesity(OR =2.018, 95% CI: 1.188-3.428) and abnormal TG(OR =3.350, 95% CI: 1.148-9.774) were associated with high risk of arteriosclerosis in the elderly after controlling for age, gender, marital status and hypertension. The results of interaction analysis showed that TG * abdominal obesity had a multiplicative interaction with atherosclerosis in the elderly(OR=3.526, 95% CI: 1.053-11.810)(P<0.05).Conclusion Abdominal obesity and abnormal TG are independent influencing factors of atherosclerosis, and abdominal obesity and blood lipid level have a multiplicative interaction effect on elderly patients with atherosclerosis.