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新疆冠心病患者血清胱抑素C的临床检测意义
引用本文:张爰媛,蔺志强.新疆冠心病患者血清胱抑素C的临床检测意义[J].检验医学与临床,2011,8(20):2479-2480,2483.
作者姓名:张爰媛  蔺志强
作者单位:1. 新疆维吾尔自治区和静县人民医院检验科,841300
2. 新疆维吾尔自治区传染病医院检验科,乌鲁木齐,830000
摘    要:目的探讨新疆维吾尔族和汉族冠心病患者血清胱抑素C(CysC)的临床检测价值。方法分别检测90例维吾尔族、104例汉族冠心病患者和120例健康人血清CysC、尿素氮(BUN)、肌酐(Cr)、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度胆固醇(LDL-C)和脂蛋白aLP(a)]水平。冠心病患者据冠状动脉造影结果分为3组:稳定型心绞痛组85例(Ⅰ)、不稳定型心绞痛组68例(Ⅱ)、心肌梗死组41例(Ⅲ),并进行组间对比分析。结果血清CysC水平与对照组相比,Ⅱ、Ⅲ组均增高,且Ⅲ组高于Ⅱ、Ⅰ组,差异均有统计学意义(P<0.05);血清BUN水平Ⅲ组高于对照组(t=11.2,P<0.05);血清LP(a)水平Ⅱ、Ⅲ组显著高于对照组,而HDL-C低于对照组(t=13.5、22、8.3,P<0.05);血清Cr、TG、TC、LDL-C水平Ⅰ、Ⅱ、Ⅲ与对照组比较差异无统计学差异(P>0.05);女性维吾尔族患者血清CysC、男性汉族患者血清LP(a)水平均增高(t=21、9.5,P<0.05)。结论血清CysC水平对新疆维吾尔族和汉族冠心病患者肾功能的监测有重要意义,可作为一个敏感指标。

关 键 词:胱抑素C  冠心病  新疆

Clinical significance of measuring serum cystain in patients with coronary heart disease in Xinjiang
ZHANG Yuan-yuan,LIN Zhi-qiang.Clinical significance of measuring serum cystain in patients with coronary heart disease in Xinjiang[J].Laboratory Medicine and Clinic,2011,8(20):2479-2480,2483.
Authors:ZHANG Yuan-yuan  LIN Zhi-qiang
Institution:1.Department of Clinical Laboratory,People′s Hospital of Hejing County,Xinjiang 841300,China;2.Department of Clinical Laboratory,Contagious Hospital of Xinjiang,Urumqi 830000,China)
Abstract:Objective To study the clinical detection value of serum cystain C(CysC) in Uygur and Han patients with coronary heart disease in Xinjiang.Methods We detected the level of CysC,blood urea nitrogen(BUN),creatinine(Cr),triglycerides(TG),total cholesterol(TCH),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),and lipoprtein(a) in the serums of 90 Uygur and 104 Han patients with coronary heart disease,as well as 120 healthy people.All patients were divided into three groups ...
Keywords:cystatin C  coronary heart disease  Xinjiang  
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