| 组织工程技术在创面修复中的应用 |
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| 引用本文： | 姜笃银,潘伊,邱道静.组织工程技术在创面修复中的应用[J].中华损伤与修复杂志,2019,14(4):241-244. |
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| 作者姓名： | 姜笃银 潘伊 邱道静 |
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| 作者单位： | 1. 250033 济南，山东大学第二医院急诊医学中心、整形烧伤外科
2. 250033 济南，山东大学第二医院急诊医学中心、整形烧伤外科；100043 中国医学科学院，北京协和医学院整形外科医院 |
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| 基金项目： | 国家自然科学基金(81372074，81071560，81873934); 山东省科技攻关项目(2015GSF118041); 山东省重点研发计划(2019GGX105011); 济南市科技攻关项目(201704129) |
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| 摘 要： | 烧创伤等原因引起的大面积皮肤缺损是修复重建外科的一大难题。传统皮肤移植术往往组织来源受限，且存在供皮区损伤等缺点。组织工程技术的进步和商品化皮肤的临床应用，为大面积烧伤和难治性创面修复提供了新的治疗手段。本文回顾组织工程技术在创面修复领域的研究进展，并分析其在研发和转化过程中的关键问题，以期为人类皮肤的功能化构建提供新思路。
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| 关 键 词： | 组织工程 皮肤 干细胞 创面修复 组织再生 |
| 收稿时间： | 2019-07-05 |
Application of tissue engineering technology in wound repair |
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| Duyin Jiang,Yi Pan,Daojing Qiu.Application of tissue engineering technology in wound repair[J].Chinese Journal of Injury Repair and Wound Healing,2019,14(4):241-244. |
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| Authors: | Duyin Jiang Yi Pan Daojing Qiu |
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| Institution: | 1. Emergency Medical Center, Department of Burns and Plastic Surgery, the Second Hospital of Shandong University, Jinan 250033, China
2. Emergency Medical Center, Department of Burns and Plastic Surgery, the Second Hospital of Shandong University, Jinan 250033, China; Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100043, China |
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| Abstract: | Large skin defects caused by burns or trauma are a major problem in repair and reconstruction surgery. Traditional skin graft often has limited tissue sources and has disadvantages such as damage to the donor site. With the development of tissue engineering, commercial artificial skin has been applied in practice, providing a new therapy for refractory ulcers. This article reviews the research progress of tissue engineering technology in the field of wound repair, and analyzes its key problems in the process of research and development, in order to provide new ideas for the functional construction of human skin. |
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| Keywords: | Tissue engineering Skin Stem cells Wound repair Tissue regeneration |
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