| 维拉帕米抑制气管插管时心血管反应的效应 |
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| 引用本文： | 刘凌云,方真,金士翱. 维拉帕米抑制气管插管时心血管反应的效应[J]. 华中科技大学学报(医学版), 1997, 0(Z1) |
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| 作者姓名： | 刘凌云 方真 金士翱 |
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| 作者单位： | 同济医科大学附属同济医院麻醉学教研室，同济医科大学附属同济医院麻醉学教研室，同济医科大学附属同济医院麻醉学教研室 武汉 430030，武汉 430030，武汉 430030 |
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| 摘 要： | 观察不同剂量维拉帕米对减弱气管插管时心血管反应的效应。选择符合美国麻醉医师学会(ASA)Ⅰ级标准需全麻插管的患者30例,在窥喉前45s静脉给予维拉帕米0.05 mg/kg(A组)或0.1mg/kg(B组)或生理盐水(C组),麻醉诱导用25.0g/L硫喷妥纳(5 mg/kg)、维库溴铵O.2 mg/kg。结果表明,维拉帕米虽不能预防窥喉和插管时引起的心动过速,但与对照组比较可明显抑制平均动脉压(MAP)的增高(P<0.05)。
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| 关 键 词： | 维拉帕米 气管插管 高血压 心血管反应 |
Effect of Verapamil on the Cardiovascular Responses to Tracheal Intubation |
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| Liu Lingyun,Fang Zhen,Jin Shiao. Effect of Verapamil on the Cardiovascular Responses to Tracheal Intubation[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1997, 0(Z1) |
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| Authors: | Liu Lingyun Fang Zhen Jin Shiao |
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| Affiliation: | Liu Lingyun,Fang Zhen,Jin Shiao,Department of Anesthesiology,Tongji Hospital,Tongji Medical University,Wuhan 430030 |
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| Abstract: | The efficacy of verapamil in attenuating the cardiovascular responses to tracheal intubation was examined in 30 of ASA I patient by giving verapamil 0. 05 mg/kg (group A) or 0. 1 mg/kg (group B) or Natrual salme (group C) intravenously 45 s before laryngoscopy. Anesthesia was induced with 25.0 g/L thiopentone 5 mg/kg i.v. and tracheal intubation was facilitated with vencuronium 0. 2 mg/kg. The increase of MAP was obviously inhibited in verapanmil-treated patients compared with those in the control group (P< 0. 05), although verapamil failed to prevent tachycardia caused by laryngoscopy and intubation |
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| Keywords: | verapamil tracheal intubation high arterial pressure cardiovascular responses |
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