我院恶性肿瘤患者院内感染及抗菌药使用的回顾性分析

目的了解我院恶性肿瘤患者院内感染及抗菌药使用情况,以进一步合理使用抗菌药,降低院内感染的发生。方法回顾性分析我院482例住院恶性肿瘤患者院内感染的发生情况,分析发病率、发病部位、病原学检测及抗菌药使用情况。结果住院的482例患者中,发生院内感染99例,感染率为20.5%。院内感染者中上呼吸道感染最多,占26%(26/99);病原学送检率为39%(39/99),培养或(和)涂片病原学阳性率82%,其中G~-细菌占57%,G~+细菌占24%,真菌占19%;抗菌药使用率95%,其中以头孢菌素类使用率最高,占43%。联合放、化疗者院内感染的发生率高于单纯放疗或化疗者(52.9%vs.16.4%、25.1%,均P<0.05)。结论进一步加强院内感染的监测、及时进行病原学检测和药敏试验、合理使用抗菌药等措施有利于恶性肿瘤患者院内感染的防治。

Retrospective study on nosocomial infection and use of anti-bacterial agents in malignant tumor patients in our hospital

AIM To evaluate the nosocomial infection and use of anti-bacterial agents in hospitalized cancer patients so as to make use of antibiotics reasonably and reduce the infect rate.METHODS Retrospective study on nosocomial infection of 482 malignant tumor patients in our hospital was be done,including the incidence of the disease,disease location,etiology detecting and use of anti-bacterial agents.RESULTS There were 99 patients suffered from nosocomial infection in 482 patients hospitalized,with the incidence 2...