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胰岛素在急性冠脉综合征伴高血糖症中的应用
引用本文:黄震华. 胰岛素在急性冠脉综合征伴高血糖症中的应用[J]. 中国新药与临床杂志, 2011, 0(10)
作者姓名:黄震华
作者单位:上海交通大学医学院附属第九人民医院心血管病研究室;
摘    要:葡萄糖、胰岛素、氯化钾用于急性心肌梗死已有多年历史。近年来观察到高血糖有致炎症作用,而胰岛素有抗炎症和抗动脉粥样硬化作用。急性心肌梗死时合用葡萄糖、胰岛素、氯化钾应避免引起患者高血糖。实验研究和临床研究观察到在急性冠脉综合征和急性心肌梗死时使用胰岛素可缩小心肌梗死范围,改善患者预后。

关 键 词:胰岛素  氯化钾  葡萄糖  动脉粥样硬化  炎症  急性冠脉综合征

Using insulin in treatment of acute coronary syndrome accompanying hyperglycemia
HUANG Zhen-hua. Using insulin in treatment of acute coronary syndrome accompanying hyperglycemia[J]. Chinese Journal of New Drugs and Clinical Remedies, 2011, 0(10)
Authors:HUANG Zhen-hua
Affiliation:HUANG Zhen-hua(Cardiovascular Research Room,the Ninth People's Hospital,Medical College,Shanghai Jiaotong University,SHANGHAI 200011,China)
Abstract:Glucose,insulin,kalium chloride has been used for acute myocardial infarction for many years.Recently it was observed that hyperglycemia had proinflammatory effect,and insulin had anti-inflammatory and anti-atherosclerotic effects.When combined use of glucose,insulin and kalium chloride in the treatment of acute myocardial infarction,hyperglycemia should be avoided.The experimental and clinical study showed that insulin might decrease infarct size and improve prognosis.
Keywords:insulin  potassium chloride  glucose  atherosclerosis  inflammation  acute coronary syndrome  
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