干燥性与萎缩性鼻炎鼻黏液纤毛传输功能的比较

目的 :观察干燥性鼻炎与萎缩性鼻炎鼻黏液纤毛传输功能的变化 ,并研究二者的差异和鉴别诊断标准。方法 :用糖精法测定 6 5例干燥性鼻炎患者 (干燥鼻炎组 )、2 5例萎缩性鼻炎患者 (萎缩鼻炎组 )及 2 0例无鼻病患者 (正常对照组 )的鼻黏液纤毛传输速率 (MTR) ,并进行比较 ;观察吉诺通对 2 5例干燥性鼻炎患者的症状、体征及MTR的影响。结果 :正常对照组MTR[(9.15± 0 .86 )mm/min]明显高于干燥鼻炎组 [(5 .84± 0 .4 8)mm/min]和萎缩鼻炎组 [(3.36± 0 .0 7)mm/min],其差异均有极显著性意义 (均P <0 .0 1) ;干燥鼻炎组明显高于萎缩鼻炎组 ,其差异亦有极显著性意义 (P <0 .0 1)。 2 5例干燥性鼻炎患者经吉诺通治疗 2周后 ,自觉症状减轻 ,但MTR无显著变化 (P >0 .0 5 )。结论 :干燥性鼻炎是不同于萎缩性鼻炎的一种独特性鼻部疾病 ,对其深入研究 ,探讨有效治疗方法很有意义

Comparison of the mucociliary transport rate of rhinitis sicca and atrophic rhinitis

OBJECTIVE: To study the mucociliary transport function of rhinitis sicca and atrophic rhinitis, and to explore the standard of diagnosis. METHOD: The MTR of normal control group, the rhinitis sicca group and the atrophic rhinitis were determined by using saccharin, and then compared. Then MTR of rhinitis sicca treatment group were compared before and after treatment. RESULT: The MTR of normal group: (9.15 +/- 0.86) mm/min; the rhinitis sicca group: (5.84 +/- 0.48) mm/min and the atrophic rhinitis group: (3.36 +/- 0.07) mm/min. There were significant difference among them (P < 0.05). 25 patients of rhinitis sicca were treated by administering the pill of Gelomyrtol forte in 2 weeks. The MTR of rhinitis sicca were no significant difference before and after treatment (P > 0.05). CONCLUSION: Rhinitis sicca is a separate nasal disease, which is different from atrophic rhinitis. It is important to find an effective treatment for the disease.