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吸入速尿对致敏原乙酰胆碱和组胺混合液诱发哮喘的保护效应
引用本文:戴伟娟,辛勤,李健美,凌秀珍. 吸入速尿对致敏原乙酰胆碱和组胺混合液诱发哮喘的保护效应[J]. 济宁医学院学报, 1997, 0(4)
作者姓名:戴伟娟  辛勤  李健美  凌秀珍
作者单位:济宁医学院药理学教研室
摘    要:本研究采用整体实验方法 ,观察了速尿对致敏原、药物诱发哮喘的保护效应。结果表明 :吸入速尿能明显延长鸡卵蛋白、乙酰胆碱和组胺混合液所诱发哮喘的潜伏期 ,与给药前或对照组比较差异非常显著。认为本药具有良好的平喘作用。这不仅为哮喘的治疗又开新途径 ,而且有助于进一步阐明哮喘的发病机理

关 键 词:速尿  哮喘  鸡卵蛋白  乙酰胆碱  组胺

PROTECTIVE EFFECT OF INHALED FUROSEMIDE ON ALLERGEN AND ACHHISTAMINE INDUCED ASTHMATIC REACTIONS
Dai Weijuan,Xin Qin,Li Jianmei,et al.. PROTECTIVE EFFECT OF INHALED FUROSEMIDE ON ALLERGEN AND ACHHISTAMINE INDUCED ASTHMATIC REACTIONS[J]. Jounal of Jinning Medical College, 1997, 0(4)
Authors:Dai Weijuan  Xin Qin  Li Jianmei  et al.
Abstract:The purpose this study was to observe the protective effect of inhaled furosemide on allergen,histamine and Ach induced asthmatic reactions. The results showed that inhaled furosemide could significantly inhibied the asthmatic response of guinea pigs,which was induced by Ach histamine and a specific allergen. The latent period of induced asthma was markedly prolonged by inhaled furosemide. Mechanisms of these phenomena will require further investigation.
Keywords:Furosemide  Ach  Histamine  Asthma  Ovalbumin.  
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