Co-transplantation of Schwann cells and bone marrow stromal cells versus single cell transplantation on repairing hemisected spinal cord injury of rats |
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| Authors: | Jifei Zhang Geng Wu Fusheng Zhao Xiudong Jin |
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| Institution: | Jifei Zhang1,Geng Wu2,Fusheng Zhao1,Xiudong Jin3 1Department of Histology and Embryology,Mudanjiang Medical College,Mudanjiang 157011,Heilongjiang Province,China 2Clinical Skills Training Center,China 3Department of Physiology,China |
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| Abstract: | BACKGROUND: Bone marrow stromal cells (BMSCs) or Schwann cells (SCs) transplantation alone can treat spinal cord injury. However, the transplantation either cell-type alone has disadvantages. The co-transplantation of both cells may benefit structural reconstruction and functional recovery of spinal nerves. OBJECTIVE: To verify spinal cord repair and related mechanisms after co-transplantation of BMSCs and SCs in a rat model of hemisected spinal cord injury. DESIGN, TIME AND SETTING: A randomized, controlle... |
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| Keywords: | bone marrow stromal cells Schwann cells co-transplantation spinal cord injury neural regeneration |
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