The distribution of alkaline and acid phosphatase in the liver of white rats during irradiation with the radioactive isotope of iron Fe59

Summary The distribution of the acid and alkaline phosphatase was studied in the liver of white rats irradiated internally with radioactive iron Fe⁵⁹. For 6 days 25–45 C per day of Fe⁵⁹ was given with food (to experimental animals). The phosphatases were examined by the Gomori's method.In control rats alkaline phosphatase was revealed in the nuclei of hepatic cells. High concentrations of the enzyme were noted in the leucocytes and the walls of the blood capillaries. The acid phosphatase was found in the nuclei of hepatic cells, endothelium of blood capillaries and in the epithelium of the bile interiobular ducts.Following a 6-day irradiation with Fe⁵⁹ an increase of the alkaline phosphatase activity along with the rise in the number of hepatic tissue elements containing it was observed. Acid phosphatase localization and its activity remain without any visible changes.Presented by Active Member Acad. Med. Sci. USSR, V. N. Chernigovskii