新生儿缺氧缺血性脑病血浆血小板活化因子测定及临床意义

目的探讨新生儿缺氧缺血性脑损伤(HIBD)时血浆血小板活化因子(PAF)水平的变化。方法90名缺氧缺血性脑病(HIE)患儿及同期住院50名新生儿各抽取静脉血2 mL,用薄层层析法测定PAF水平。结果不同临床分度HIE患儿血浆PAF水平与对照组PAF比较差异均有统计学意义(P<0.01)。结论PAF参与新生儿HIBD的全过程。

Detection of blood plasma platelet activating factor in newborns with hypoxic ischemic encephalopathy

Objective To investigate the level of platelet activating factor(PAF) in newborns with hypoxic ischemic brain damage(HIBD).Methods Ninety hypoxic ischemic encephalopathy(HIE) patients and 50 homeochronous hospitalized newborns were collected,2 mL venous blood was drawn out and PAF level was detected by thin layer chromatography.Result There was significant difference in PAF level between HIE newborns at different clinical grading and control group(P<0.01). Conclusion PAF plays a part in the whole process of...