PTEN与肿瘤的相关性研究进展 |
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引用本文: | 赵红霞.PTEN与肿瘤的相关性研究进展[J].武汉大学学报(医学版),2014,35(1):155-159. |
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作者姓名: | 赵红霞 |
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作者单位: | 赵红霞 (皖南医学院 安徽 芜湖 241002); |
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摘 要: | 抑癌基因PTEN是在1997年被发现的,具有双重特异性磷酸酶活性。该基因突变,可导致多种肿瘤的发生。本文就PTEN的研究进展及其与肿瘤的关系进行综述。
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关 键 词: | PTEN 抑癌基因 信号转导 肿瘤 |
Research Progress in PTEN and Tumor Development |
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Abstract: | Anti-oncogene PTEN was initially identified in 1997,and it has a dual-specificity phosphatase activity.Mutations of this gene mutations may lead to the occurrence of a variety of tumors. This paper reviewed on the research progress of the relationship between PTEN and tumor development. |
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Keywords: | PTEN Anti-Oncogene Signal Transduction Tumor |
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