| Ⅱ型糖尿病微血管病变患者血中超氧化物歧化酶、维生素E和过氧化脂质含量变化及其意义 |
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| 引用本文： | 张启国,唐尧.Ⅱ型糖尿病微血管病变患者血中超氧化物歧化酶、维生素E和过氧化脂质含量变化及其意义[J].东南大学学报(医学版),1994(3). |
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| 作者姓名： | 张启国 唐尧 |
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| 作者单位： | 南京铁道医学院附属医院内科 |
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| 摘 要： | 作者测定了２５例糖尿病微血管病变和１２例无微血管病变患者血中ＳＯＤ－Ｔ、ＳＯＤ－Ｍｎ、ＳＯＤ－Ｃｕ·Ｚｎ、ＶＥ、ＬＰＯ的含量。结果显示，糖尿病患者血ＳＯＤ－Ｔ、ＳＯＤ－Ｍｎ、ＳＯＤ－Ｃｕ·Ｚｎ含量明显减低（Ｐ＜０．０１），ＬＰＯ明显增高（Ｐ＜０．０１），ＶＥ含量无明显变化。但微血管病变组与无微血管病变组血中ＳＯＤ和ＬＰＯ含量无明显差异。提示糖尿病微血管病变患者血中ＳＯＤ、ＬＰＯ的含量变化系糖尿病本身的变化特征，而不是糖尿病微血管病变的结果。
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| 关 键 词： | 糖尿病 微血管病变 超氧化物歧化酶 维生素E 过氧化脂质 |
CHANGES IN CONTENTS OF SOD,Ve AND LPO IN TYPE II DIABETICS WITH MICROANGIOPATHY
AND THEIR CLINICAL SIGNIFICANCE |
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| Zhang Qiguo,Tang Yao.CHANGES IN CONTENTS OF SOD,Ve AND LPO IN TYPE II DIABETICS WITH MICROANGIOPATHY
AND THEIR CLINICAL SIGNIFICANCE[J].Journal of Southeast Univ: Medical Sci Ed,1994(3). |
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| Authors: | Zhang Qiguo Tang Yao |
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| Abstract: | evels of
SOD. VE and LPO were analyzed in 25 diabetics with microangiopathy and 12 cas-es without
microangiopathy. The results showed that the contents of SOD-T. SOD-Cu,Zn.SOD-Mn were
lowered significantly(P<0.01),LPO highered(P<0.01) VE unchanged in dia-betes. No significant
difference was noted in the contents of SOD and LPO between diabetics withmicroangiopathy
and those without.The changes in contents of SOD ,LPO in diabetics with mi-croangiopathy may
be characteristic of diabetes mellitus and are not the results of diabetic mi-croangiopathy. |
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| Keywords: | diabetes mellitus microangiopathy superoxide dismutase vitamin E lipid perox-ide |
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