Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea |
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| Authors: | Boakye Paul A Brierley Stuart M Pasilis Sofie P Balemba Onesmo B |
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| Affiliation: | Department of Biological Sciences, Australia. |
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| Abstract: | Ethnopharmacological relevance: The extract from the stem bark of Garcinia buchananii trees is used as an anti-diarrhea remedy in sub-Saharan Africa. We tested the hypothesis that G. buchananii bark extract and its anti-motility fractions are effective treatments against lactose-induced diarrhea. |
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| Keywords: | ext., Extract G. buchananii, Garcinia buchananii g/L, Gram/Liter HCA, (−) – Hydroxycitric acid HLD, High lactose diet h, Hours 5-HT, 5-hydroxytryptamine (serotonin) LD, Lactose-induced diarrhea LP, Loperamide mg/L, Milligram/liter OD, Osmotic diarrhea ORS, Oral rehydration solution PTLC, Preparative thin layer chromatography SD, Standard chow diet UNICEF, United Nations Children's Fund vs., Versus WHO, World Health Organization |
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