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肠外高营养治疗重症溃疡性结肠炎119例分析
引用本文:许昌泰,郭学刚,孙安华,李彩宁,张宏博,周新民,潘伯荣.肠外高营养治疗重症溃疡性结肠炎119例分析[J].天津医药,2005,33(12):762-764.
作者姓名:许昌泰  郭学刚  孙安华  李彩宁  张宏博  周新民  潘伯荣
作者单位:1. 710032,第四军医大学学报编辑部
2. 西京医院全军消化病研究所
基金项目:陕西省卫生厅基金资助项目(项目编号:2004D26)
摘    要:目的:观察肠外高营养对重症溃疡性结肠炎临床治疗效果。方法:对119例重症溃疡性结肠炎患者采取肠外静脉补充足够的营养,完全胃肠道休息。同时于治疗前后进行组织学检查。结果:经过4周治疗后临床痊愈36例(30.3%),好转65例(54.6%),无效18例(15.1%),总有效率84.9%。全部患者血清谷草转氨酶和谷丙转氨酶在正常范围,血清白蛋白治疗后明显好转(P〈0.05),组织学也明显改善。结论:重症溃疡性结肠炎肠外静脉高营养疗法是一种安全、有效可行的方法,同时可以促进组织学恢复。

关 键 词:胃肠外营养    结肠炎  溃疡性  危重病
收稿时间:11 8 2004 12:00AM
修稿时间:2004-11-082005-08-05

Clinical Analysis of Parenteral Hyperalimentation in 119 Severe Ulcerative Colitis Patients
XU Changtai,GUO Xuegang,SUN Anhua,LI Caining,ZHANG Hongbo,ZHOU Xinmin,PAN Borong.Clinical Analysis of Parenteral Hyperalimentation in 119 Severe Ulcerative Colitis Patients[J].Tianjin Medical Journal,2005,33(12):762-764.
Authors:XU Changtai  GUO Xuegang  SUN Anhua  LI Caining  ZHANG Hongbo  ZHOU Xinmin  PAN Borong
Abstract:Objective: To study the clinical effects of parenteral hyperalimentation in severe ulcerative colitis patients. Methods: Parenteral hyperalimentation and complete gastrointestinal tract rest were given in 119 severe ulcerative colitis patients, and the histology examinations were studied before and after therapy. Results: After 4 weeks' therapy, 36 cases fully recovered (30.3%), 65 cases improved (54.6%), 18 cases inefficient (15.1%), and the total effective rate was 84.9%. Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were in common range in all patients, the serum albumin significantly increased (P < 0.05), and the histology significantly improved. Conclusion: The parenteral hyperalimentation therapy is a safe and effective method for severe ulcerative colitis patients, and it can improve the histology of patients.
Keywords:parenteral nutrition  total colitis  ulcerative critical illness
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