中药威灵仙的原植物和生药学研究

通过对全国威灵仙主要产区进行调查,发现有四科十多种原植物。在此基础上做了毛茛科威灵仙的药材性状、显微鉴定以及化学定性、定量分析的研究。结果表明;它们的药材性状和组织构造均有区别,但主要的化学成分极为相近。

BOTANICAL AND PHARMACOGNOSTICAL STUDIES OF THE CHINESE DRUG WEI-LING-XIAN

Wei-Ling-Xian is a Chinese traditional drug widely used for the treatment of rheumatism.A recent survey of the drug market revealed, however, that the drug under the general name "Wei-Lin-gXian" involves many plants of different origins. They belong to 4 families, 5 genera and at least 14 species (cf. Tab. 1), but ethnopharmacologically. they have been shown to possess similar actions.This paper reports those drugs derived from the Clematis genus. Comparing the morphological and histological characters of 9 species of Clematis, viz., C. chinensis, C. unicinata, C. finetiana, C. meyeniana, C. hexapetala, C. manshurica, C. paniculata, C. florida and C, lasiandra, the result showed that they can be distinguished more obviously in histology.By means of TLC and a quantitative spectrophotometric method, all these 9 species were shown tocontain anemonine, amounting to 0.314～4.376% depending on the species of the plants, and the condition of the sample and supposed to contain oleanolic acid after hydrolysis of the saponin present, as shown by direct comparison with the authentic sample.In addition, two analytical keys for the drugs and original plants, respectively, together with 6 figures and 2 plats are here presented.