针刺治疗偏头痛的Meta分析

目的系统评价针刺疗法治疗偏头痛的有效性。方法计算机检索PubMed、EMbase、中国生物医学文献数据库（CBM）、中国期刊全文数据库（CNKI）、中文科技期刊数据库（VIP）和万方数据库,并辅以文献追溯及手工检索的方法,收集公开发表的所有关于针刺治疗偏头痛的随机对照试验（RCT）。检索年限为2000年1月1日-2010年12月31日。按照纳入、排除标准筛选文献并评价纳入研究质量后,应用RevMan5.1软件进行Meta分析。结果共纳入33篇RCT,对照组为西药的28篇,对照组为中药的3篇,对照组为安慰针刺的3篇（其中1篇文献对照组既有安慰针刺,又有西药）。Meta分析结果显示,针刺组治疗偏头痛有效率优于西药组RR=1.24,95%CI（1.16,1.34）,P〈0.00001],优于中药组RR=1.29,95%CI（1.14,1.45）,P〈0.00001],优于安慰针刺组RR=1.87,95%CI（1.17,2.98）,P=0.009]。结论目前研究提示,针刺治疗偏头痛的有效率高于西药、安慰针刺及中药治疗,但高质量、大样本的研究相对不足,需要进一步证实。

Acupuncture for Migraine:A Meta Analysis

Objective To evaluate the effectiveness of acupuncture treatment for migraine.Methods The randomized controlled trials(RCTs) in PubMed,EMbase,CBM,CNKI,VIP and WanFang database from January 1,2000 to December 31,2010 were electronically searched,and the references in relevant reviews were also manually searched.The quality of the included studies was assessed.Two reviewers independently screened the trials according to inclusion and exclusion criteria,extracted the data,and assessed the methodology quality.Meta-analysis was performed using the Cochrane Collaboration’s RevMan 5.1 software.Results Thirty-three RCTs were finally included.The results of meta-analysis showed that compared with western medicine 28 RCTs,RR=1.24,95%CI(1.16,1.34),P<0.000 01],Chinese medicine 3 RCTs,RR=1.29,95%CI(1.14,1.45),P<0.000 01],and placebo acupuncture (3 RCTs,RR=1.87,95%CI(1.17,2.98),P=0.009],the improvement rates of acupuncture were significantly higher.Conclusions This study shows the improvement rates of acupuncture for migraine are higher than western medicine,Chinese medicine and placebo acupuncture,but it needs more higher quality of RCTs to enforce.