胃间质瘤的腹腔镜手术与开腹手术的临床对比研究

目的比较腹腔镜胃间质瘤切除术与开腹胃间质瘤切除术的临床疗效，探讨腹腔镜技术在胃间质瘤治疗中的应用价值。方法选择2005年3月至2007年12月于中国医科大学附属盛京医院行胃间质瘤切除术的患者54例，其中男性32例，女性22例，男女比例为1．5：1；年龄29-70岁，平均年龄51．6岁。根据患者意愿分为腹腔镜手术组（19例）和传统开腹手术组（35例），回顾性分析两组患者的临床和病理资料，对比两组的手术安全性、术后恢复情况、随访结果。结果两组均无术中、术后严重并发症和手术死亡病例；腹腔镜手术组手术时间为（68．0±11．0）min，与开腹手术组（66．0±9．0）min相比无明显差距：腹腔镜手术组术中失血量为（43．0±14．0）ml，显著少于开腹手术组（155．0±55．0）ml；术后排气时间和住院天数腹腔镜手术组为（25．2±6．9）h、（5．2±1．7）d，显著短于开腹手术组（37．6±8．4）h、（8．4±3．3）d。两组短期（3—12个月）累计生存率比较差异无统计学意义（P〉0．05）。结论腹腔镜胃间质瘤切除术安全、有效，具有可行性。

Clinical comparitive study on laparoscopic vs open resection in gastric stromal tumors

Objective To compare the result of laparoscopic and open resection for gastric stromal tumors. Methods A total of 54 patients （male 32, female 22, aged 29 - 70 years, mean age 51.6 years） with gastric stromal tumors from March 2005 to December 2007 were divided into 2 groups： laparoscopy group and open resection group. The operation security, postoperative recovery and follow-up results of these patients were compared. Results There were 19 patients performed laparoseopie resection, 35 patients treated by open resection In both groups no severe complications and death ease were found. The operation time oflaparoseopy group （68.0± 11.0） min were similar to that in open resection group （66.0 ± 9.0） min; the blood loss in laparoscopy group （43.0 ± 14.0） ml was markedly less than open resection group（155.0 ± 55.0） ml; exhaust time and length of hospital stay after operation in laparoscopy group were （25.2 ± 6.9） hours and （5.2 ± 1.7） days respectively, which were significantly shorter than those in open resection group （37.6 ± 8.4） hours and （8.4 ± 3.3） days （P〈0.05）.Short-term cumulative survival rates of 2 groups had nosignificant difference（P〈0.05）. Conclusion Laparoscopic resection of gastric stromal tumors could be performed safely and effectively with the advantage of minimal invasiveness.