肺癌化疗患者心理弹性特点及与疲乏程度的相关性研究

目的 探讨肺癌化疗患者心理弹性水平与癌因性疲乏程度的危险因素及相关性分析。方法 选择我院2018年1月—2019年4月收治的167例肺癌化疗患者为研究对象，采用CD-RISC量表评价患者的心理弹性水平、PFS量表评价癌因性疲乏程度，并分析CD-RISC评分、PFS评分与患者临床资料的关系，Logistic回归分析其独立危险因素，Pearson法分析心理弹性水平与癌因性疲乏程度的相关性。结果 年龄、居住地、婚姻状况、文化程度及付费方式为肺癌化疗患者心理弹性水平的独立危险因素（P<0.05）；年龄、居住地、婚姻状况、化疗次数为肺癌化疗患者癌因性疲乏程度的独立危险因素（P<0.05）；乐观、坚韧、自强、生活满意度等心理弹性特点及CD-RISC总评分与PFS评分均呈负相关（r分别为-0.557、-0.612、-0.548、-0.604、-0.587，P<0.05）。结论 肺癌化疗患者心理弹性水平与癌因性疲乏程度显著相关，临床治疗和护理过程中应关注患者的心理弹性水平及癌因性疲乏，及时给予指导，以改善其不良心理状况，减轻癌因性疲乏程度，从而提高其生活质量，改善预后。

Psychological resilience of lung cancer patients with chemotherapy and its relation with fatigue degree

Objective To explore the risk factors of psychological resilience and cancer-related fatigue of lung cancer patients with chemotherapy, and to analyze the correlation between psychological resilience and cancer-related fatigue.Methods A total of 167 lung cancer patients treated with chemotherapy in our hospital between January 2018 and April 2019 were selected. They were investigated with the Connor-Davidson Resilience Scale (CD-RISC) to test the level of resilience and the revised Piper Fatigue Scale (PFS) to evaluate the degree of cancer-related fatigue. The relationship of the CD-RISC score and PFS score was analyzed with the clinical characteristics of patients. The independent risk factors were analyzed by Logistic regression. The correlation between the level of psychological resilience and the degree of cancer-related fatigue was analyzed with the Pearson''s correlation coefficient.Results The age, place of residence, marital status, educational level and payment mode were independent risk factors for the resilience level of lung cancer patients receiving chemotherapy (P<0.05), while the age, place of residence, marital status and frequency of chemotherapy were independent risk factors for their cancer-related fatigue level (P<0.05). The scores of the four dimensions of psychological resilience as optimism, tenacity, self-improvement and life satisfaction, and the total score of CD-RISC were negatively correlated with the PFS score (r=-0.557, -0.612, -0.548, -0.604, -0.587, respectively, P<0.05).Conclusion Psychological resilience level of patients with lung cancer undergoing chemotherapy is significantly correlated with their degree of cancer-related fatigue. In clinical treatment and nursing work, it is necessary to pay more attention to the patients'' psychological resilience level and the degree of cancer-related fatigue, and to give guidance timely to improve the adverse psychological status and alleviate the fatigue, so as to improve the prognosis of patients.