糖尿病视网膜病变374例临床分析

目的　探讨糖尿病视网膜病变 (DR)的临床特点。方法　 1将 374例患者分为非糖尿病视网膜病变 (NDR)、背景型糖尿病视网膜病变 (BDR)、增生型糖尿病视网膜病变 (PDR)三组 ,分析比较三组的临床指标。2将 374例患者分别分为肥胖组、非肥胖组 ;高血压组、非高血压组 ,分别探讨肥胖及高血压对 DR发病率的影响。结果　 1HDR、BDR、PDR三组病程、糖化血红蛋白 (Hb A1 c)、血脂代谢紊乱程度差异均有显著性。 2肥胖组DR发病率显著高于非肥胖组。 3高血压组 DR发病率显著高于非高血压组。结论　糖尿病病程、血糖控制程度、血脂代谢紊乱、肥胖、高血压等因素均在 DR的发生发展中起一定作用。

A clinical analysis of 374 cases of diabetic retinopathy

Objective To investigate the clinic features of diabetic retinopathy (DR).Methods 374 cases of diabetes mellitus (DM) were collected from the First Hospital of Xi′an Jiaotong University.①The cases were divided into 3 groups according to prevalence and severity of DR,i.e.nondiabetic retinopathy (NDR) group,background diabetic retinopathy (BDR) group,and proliferative diabetic retinopathy (PDR) group.②The cases were divided into non obesity group and obesity group according body mass index (BMI),comparing the incidence of DR between the two groups.③The cases were also divided into non hypertension group and hypertension group,compareing the incidence of DR between the two groups.Results ①There existed apparent differences of glycosylated hemoglobin (HbA_1c),dyslipidemia among the three groups during their DM period.②The DR incidence in obesity group was significantly higher than in non obesity group.③The DR incidence in hypertension group was higher than in non hypertension group.Conclusion Duration of DM,HbA_1c,dyslipidemia,obesity,hypertension all play a role in the onset and development of DR to some extent.