脑弥漫性轴索损伤的治疗效果分析

目的探讨脑弥漫性轴索损伤（DAI）的发病机制、临床特点、诊断、有效治疗措施和预后，提高临床治疗成功率及临床生存质量。方法回顾性分析35例DAI患者的受伤方式、格拉斯哥昏迷（glasgow come scale，GCS）评分、影像学特征、并发症及治疗方法和预后。结果伤后6个月根据格拉斯哥结局量表（glasgow outcomescale，GOS）进行预后评分：死亡7例，植物生存5例，重残8例，中残5例，轻残4例，良好6例。结论人院时GCS评分越低，患者昏迷持续时间越长，预后越差，病死率、致残率和植物生存率越高；早期综合治疗结合高压氧及尽早康复功能介入等可改善预后。

Diagnosis and Treatment Analyses of Severe Diffuse Axonal Injury

Objective To study the pathogenesis,clinical characteristics,diagnosis,treatment and prognosis of severe diffuse axonal injury （DAD. Methods Clinical data of 35 cases with severe DAI were retrospectively analyzed according to Glasgow come scale（GCS） assessment. Results According to the glasgow outcome scale （GOS） 6 months after the injury,final outcome in patients were divided into 6 categories： good recovery （6 cases, 17.14%）, gently disability （4 cases, 11.43% ） , moderate disability （ 5 cases, 14.29% ）, severe disability （ 8cases, 22. 86%） ,vegetative state （Scases,14.29%） and death （7cases,20.00%）. Conclusion The lower the GCS value and the longer the persistent time of coma, the poorer the prognosis and the higher rate of mortality, diability. Early comprehensive treatment for DAI with hyperbaric oxygen and early intervention of rehabilitation can improve prognosis significantly.