影响女性肝细胞癌预后因素初步探讨

自1987年2月至1995年8月收治32例女性肝细胞癌及212例男性肝细胞癌,经随访发现,女性组术后存活期明显比男性组长。通过对两组病人临床资料的统计分析,发现其发病年龄、临床表现、术前AFP水平,HBsAg阳性率等方面无显著差异(P>0.05)。术前白:球蛋白倒置比率,r—谷氨酰转肽酶(r—GT)阳性率(≥40u)、肝癌合并肝硬变比率、肝内转移形成卫星结节的比率等方面存在着显著差异(P<0.05)。作者认为女性组肝癌合并肝硬变较少,肝功能损害较轻、肝内转移较少,以及性激素的作用是导致女性肝癌术后存活期明显比男性组长的原因。

Clinical Analasis of Prognosis Factors in Women with hepatocellular Carcinoma

From February, 1987 to Auguest 1995 32 female cases and 212 male cases of hepatocellular carcinoma (HCC) were entered for the study, the Results showed that 32 Women had higher survival rate than that in male patient. There were no significant effect of the clinical staging of HCC, positive rate of HBsAg,serum AFP level,macroscopic pathological patterns,surgical techniques on the survival rate of patient. Conclusicons. the better prognosis in women with HCC was associated with less cirrhosis,better liver function,frequent tumor encapsulation,lower tumor invasiveness and sexhomones.